Browsing by Author "Sobrevia, Luis"

Now showing items 1-4 of 4

    • Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent ... 
      Riquelme, Jaime; Westermeier, Francisco; Hall, Andrew R.; Vicencio, Jose; Pedrozo Cibils, Zully; Ibacache, Mauricio; Fuenzalida, Barbara; Sobrevia, Luis; Davidson, Sean M.; Yellon, Derek M.; Sánchez, Gina; Lavandero González, Sergio (Elsevier, 2016)
      The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can also act as a preconditioning mimetic. The ...
    • Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced ... 
      Westermeier, Francisco; Salomón, Carlos; Farías, Marcelo; Arroyo, Pablo; Fuenzalida, Bárbara; Sáez, Tamara; Salsoso, Rocío; Sanhueza, Carlos; Guzmán Gutiérrez, Enrique; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis (2015)
      Reduced adenosine uptake via human equilibrative nucleoside transporter 1 (hENT1) in human umbilical vein endothelial cells (HUVECs) from gestational diabetes mellitus (GDM) is reversed by insulin by restoring hENT1 ...
    • Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus 
      Silva, Luis; Villalobos Labra, Roberto; Toledo, Fernando; Paublo Montenegro, Mario; López Aceitón, Marcia; Salsoso, Rocio; Pardo, Fabián; Escobar Leiva, Andrea Pamela; Sobrevia, Luis; Subiabre, Mario (Elsevier, 2017)
      Pregnant women diagnosed with gestational diabetes mellitus subjected to diet (GDMd) that do not reach normal glycaemia are passed to insulin therapy (GDMi). GDMd associates with increased human cationic amino acid transporter ...
    • Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological ... 
      Leiva, Andrea; Fuenzalida, Bárbara; Westermeier, Francisco; Toledo, Fernando; Salomón, Carlos; Gutiérrez, Jaime; Sanhueza, Carlos; Pardo, Fabián; Sobrevia, Luis (Hindawi, 2016)
      Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases, the maternal plasma cholesterol level increases to above this physiological range, leading to maternal ...